Anti-Human CD152 Polyclonal Antibody

CD152多克隆抗体

This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. 
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基本信息

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货号 PA04821
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide from human protein
特异性 Widely expressed with highest levels in lymphoid tissues. Detected in activated T-cells where expression levels are 30- to 50-fold less than CD28, the stimulatory coreceptor, on the cell surface following activation.
亚型 IgG
反应性 Human
克隆
Uniprot P16410
浓度 1mg/mL
推荐稀释度 IHC 1:50-200, ELISA 1:10000-20000
配方
应用范围 IHC-p,ELISA
别名 ALPS5,CD 152,CD,CD152,CD152 antigen,CD152 isoform,Celiac disease 3,CELIAC3,CTLA 4,CTLA-4,CTLA4,CTLA4,Cytotoxic T cell associated 4,Cytotoxic T lymphocyte antigen 4,Cytotoxic T lymphocyte associated 4,Cytotoxic T lymphocyte associated 4,soluble isoform,included,Cytotoxic T lymphocyte associated antigen 4,Cytotoxic T lymphocyte associated antigen 4 short spliced form,Cytotoxic T lymphocyte associated protein 4,Cytotoxic T lymphocyte associated serine esterase 4,Cytotoxic T lymphocyte protein 4,Cytotoxic T-lymphocyte protein 4,Cytotoxic T-lymphocyte-associated antigen 4,GRD4,GSE,ICOS,IDDM12,insulin-dependent diabetes mellitus 12,Ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4,OTTHUMP00000216623
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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