Anti-Human CCRL2 Polyclonal Antibody

CCRL2多克隆抗体

This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.CCRL2 (C-C Motif Chemokine Receptor Like 2) is a Protein Coding gene. Among its related pathways are Peptide ligand-binding receptors and Chemokine Superfamily Pathway: Human/Mouse Ligand-Receptor Interactions. GO annotations related to this gene include G-protein coupled receptor activity and chemokine receptor binding. An important paralog of this gene is CCR3.
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基本信息

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货号 PA02525
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from the Internal region of human CCRL2
特异性 Expressed abundantly in immunal tissues such as spleen, fetal liver, lymph node and bone marrow. Strong expression also in lung and heart. Expressed in almost all hematopoietic cells including monocytes, macrophages, PMNs, T-cells (both CD4+ and CD8+), monocyte-derived iDCs, NK cells, and CD34+ progenitor cells. B cells expressed isoform 1 but not isoform 2. Up-regulated on synovial neutrophils of rheumatoid arthritis patients.
亚型 IgG
反应性 Human
克隆
Uniprot O00421
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:20000
配方
应用范围 WB,IF,ELISA
别名 C-C chemokine receptor-like 2,CCRL2,CCRL2,Chemokine (C-C motif) receptor like 2,Chemokine receptor CCR11,Chemokine receptor X,CKRX,CRAM A,CRAM B,CRAMA,CRAMB,FLJ55815,HCR,MGC116710,MGC34104,Putative MCP 1 chemokine receptor,Putative MCP-1 chemokine receptor
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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