Anti-Human Cav1.2 Polyclonal Antibody

Cav1.2多克隆抗体

This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits. 
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基本信息

数据文档 查看数据文档
货号 PA09634
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human CACNA1C
特异性 Expressed in brain, heart, jejunum, ovary, pancreatic beta-cells and vascular smooth muscle. Overall expression is reduced in atherosclerotic vascular smooth muscle.
亚型 IgG
反应性 Human
克隆
Uniprot Q13936
浓度 0.2 mg/mL
推荐稀释度 IHC 1:25-1:100
配方
应用范围 IHC,ELISA
别名 alpha-1 polypeptide,cardiac muscle,isoform 1,L type,CAC1C,CACH 2,CACH2,CACN 2,CACN2,CACNA1C,CACNL1A1,Calcium channel,Calcium channel cardic dihydropyridine sensitive alpha 1 subunit,Calcium channel L type alpha 1 polypeptide isoform 1 cardiac muscle,Calcium channel voltage dependent L type alpha 1C subunit,CaV1.2,CCHL1A1,DHPR alpha 1,DHPR alpha 1 subunit,LQT8,TS,Voltage dependent L type calcium channel alpha 1C subunit,Voltage dependent L type calcium channel subunit alpha 1C,Voltage gated calcium channel alpha subunit Cav1.2,Voltage gated calcium channel subunit alpha Cav1.2,Voltage gated L type calcium channel Cav1.2 alpha 1 subunit,splice variant 10*,Voltage-dependent L-type calcium channel subunit alpha-1C,Voltage-gated calcium channel subunit alpha Cav1.2
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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