Anti-Human CASP14 Polyclonal Antibody

CASP14多克隆抗体

Believed to be a non-apoptotic caspase which is involved in epidermal differentiation. Seems to play a role in keratinocyte differentiation and cornification. Probably regulates maturation of the epidermis by proteolytically processing filaggrin.
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基本信息

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货号 PA02117
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from the Internal region of human Caspase-14
特异性 Expressed in keratinocytes of adult skin suprabasal layers (from spinous layers to the stratum granulosum and stratum corneum) (at protein level). Expressed in keratinocytes of hair shaft and sebaceous glands (at protein level). In psoriatic skin only expressed at very low levels.
亚型 IgG
反应性 Human
克隆
Uniprot P31944
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, ELISA 1:40000
配方
应用范围 WB,ELISA
别名 Apoptosis related cysteine protease,CASP 14,CASP-14,CASP14,Caspase 14 apoptosis related cysteine protease,Caspase 14 precursor,Caspase-14 subunit p10,Caspase14,CASPE,MGC119078,MGC119079,MICE,Mini ICE
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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