Anti-Human BIRC7 Polyclonal Antibody

BIRC7多克隆抗体

The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. 
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基本信息

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货号 PA05005
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from the Internal region of human ML-IAP.
特异性 Isoform 1 and isoform 2 are expressed at very low levels or not detectable in most adult tissues. Detected in adult heart, placenta, lung, lymph node, spleen and ovary, and in several carcinoma cell lines. Isoform 2 is detected in fetal kidney, heart and spleen, and at lower levels in adult brain, skeletal muscle and peripheral blood leukocytes.
亚型 IgG
反应性 Human
克隆
Uniprot Q96CA5
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, ELISA 1:10000
配方
应用范围 WB,ELISA
别名 Baculoviral IAP repeat containing 7,Baculoviral IAP repeat containing protein 7,Baculoviral IAP repeat-containing protein 7,BIRC 7,birc7,BIRC7,KIAP,Kidney inhibitor of apoptosis protein,Livin,Livin inhibitor of apotosis,Melanoma inhibitor of apoptosis protein,ML IAP,ML-IAP,MLIAP,RING finger protein 50,RNF 50,RNF50
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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