The protein encoded by this gene is a member of the aldo-keto reductase superfamily. Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD(P)H-dependent oxido-reduction of carbonyl groups). Transcripts of this gene have been reported in specimens of human testis. Alternative splicing results in multiple transcript variants.AKR1E2 (Aldo-Keto Reductase Family 1 Member E2) is a Protein Coding gene. Diseases associated with AKR1E2 include Hypotrichosis 1. GO annotations related to this gene include oxidoreductase activity and 1,5-anhydro-D-fructose reductase activity. An important paralog of this gene is AKR1B1.