Anti-Human AKAP12 Polyclonal Antibody

AKAP12多克隆抗体

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
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基本信息

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货号 PA10174
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human AKAP12
特异性 Expressed in endothelial cells, cultured fibroblasts and osteosarcoma, but not in platelets, leukocytes, monocytic cell lines or peripherical blood cells.
亚型 IgG
反应性 Human
克隆
Uniprot Q02952
浓度 0.3 mg/mL
推荐稀释度 WB 1:200-1:1000, IHC 1:50-1:200
配方
应用范围 WB,IHC,ELISA
别名 A kinase (PRKA) anchor protein (gravin) 12,A kinase Anchor Protein 12,A kinase anchor protein 250kDa,A-kinase anchor protein 12,A-kinase anchor protein 250 kDa,AKA12,AKAP 12,AKAP 250,AKAP-12,Akap12,AKAP250,DKFZp686M0430,DKFZp686O0331,FLJ20945,FLJ97621,Gercelin,Gravin,Kinase scaffold protein gravin,Myasthenia gravis autoantigen,Myasthenia gravis autoantigen gravin,OTTHUMP00000017426,OTTHUMP00000017427,Src-Suppressed C Kinase Substrate,Srcs5,SSeCKS,Tsga12
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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