Recombinant Human GH1 / Growth hormone 1 Protein

The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
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基本信息

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货号 TP05611
规格 20ug,50ug,100ug…
宿主 E.coli
Accession P01241
分子大小 22.1 kDa
AP_Mol_Weight
Tag
蛋白序列 Phe27-Phe217
纯度 > 95% by HPLC
浓度
配方 PBS
别名 GH;GH-N;GH1;GHB5;GHN;Growth hormone 1;hGH-N;IGHD1B
生物学活性 Measured by its ability to promote proliferation of INS-1 cells.The ED50 for this effect is 0.2-1 ng/mL.
保存条件 4°C 短期保存 (1-2 周). 长期保存在 -20°C or -70°C. 避免反复冻融.
注意 仅用于科学研究, 不能用于疾病诊断.

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