Recombinant Human DCN1-Like Protein 1/DCUN1D1 Protein(N-6His)

DCN1-Like Protein 1 is a protein containing 1 DCUN1 domain and 1 UBA-like domain. DCN1-Like Protein 1 contains part of an E3 Ubiquitin Ligase Complex for Neddylation. It is required for Neddylation of Cullin components of E3 Cullin-RING Ubiquitin Ligase complexes. It enhances the rate of Cullins Neddylation. DCN1-Like Protein 1 recruits the NEDD8-charged E2 Enzyme to the Cullin component. DCUN1D1 is involved in the release of inhibitory effects of CAND1 on the Cullin-RING Ligase E3 complex assembly and activity. It acts also as an oncogene facilitating malignant transformation and carcinogenic progression.
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基本信息

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货号 TP05881
规格 20ug,50ug,100ug…
宿主 E.coli
Accession Q96GG9
分子大小 32.3 kDa
AP_Mol_Weight 32 kDa
Tag N-6His
蛋白序列 Met 1-Val259
纯度 > 95% by HPLC
浓度
配方 PBS
别名 DCN1-Like Protein 1; DCUN1 Domain-Containing Protein 1; Defective in Cullin Neddylation Protein 1-Like Protein 1; Squamous Cell Carcinoma-Related Oncogene; DCUN1D1; DCUN1L1; RP42; SCCRO
生物学活性
保存条件 4°C 短期保存 (1-2 周). 长期保存在 -20°C or -70°C. 避免反复冻融.
注意 仅用于科学研究, 不能用于疾病诊断.

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