Recombinant Human Baculoviral IAP Repeat-Containing Protein 5/BIRC5/Survivin Protein

Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) belongs to the IAP family. BIRC5 exists as a homodimer in the apo state and as a monomer in the CPC-bound state. BIRC5 contains one BIR repeat and is expressed only in fetal kidney and liver, and to lesser extent, lung and brain. BIRC5 functions as a multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. BIRC5 is also a component of a chromosome passage protein complex (CPC), which is essential for chromosome alignment and segregation during mitosis and cytokinesis. BIRC5 acts as an important regulator of the localization of this complex.
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基本信息

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货号 TP05153
规格 20ug,50ug,100ug…
宿主 E.coli
Accession O15392
分子大小 20.4 kDa
AP_Mol_Weight 16 kDa
Tag
蛋白序列 Met 1-Asp142
纯度 > 95% by HPLC
浓度
配方 PBS
别名 Baculoviral IAP Repeat-Containing Protein 5; Apoptosis Inhibitor 4; Apoptosis Inhibitor Survivin; BIRC5; API4; IAP4
生物学活性
保存条件 4°C 短期保存 (1-2 周). 长期保存在 -20°C or -70°C. 避免反复冻融.
注意 仅用于科学研究, 不能用于疾病诊断.

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