CIAO1 Antibody (Clone AT6C9)

CIAO1 is a essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. It is a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. CIAO1 seems to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation. As part of the mitotic spindle-associated MMXD complex, it may play a role in chromosome segregation.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01176
Size 100 µL
Host Type Mouse
Immunogen Recombinant human CIAO1 (1-339aa) purified from E. coli
Specificity
Isotype IgG1,k
Reacitivity Human
Clone Anti-human CIAO1 mAb, clone AT6C9, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CIAO1 protein.
Uniprot
Concentration 1 mg/ml
Dilution
Formulation Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application ELISA, WB.
Other Names Probable cytosolic iron-sulfur protein assembly protein CIAO1, CIA1, WDR39.
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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