Anti-Rat IkB alpha Polyclonal Antibody

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01995
Size 100μl
Host Type Rabbit
Immunogen Recombinant human NF-kappa-B inhibitor alpha protein
Specificity
Isotype IgG
Reacitivity Rat
Clone
Uniprot P25963
Concentration 2 mg/mL
Dilution IHC 1:50-1:100
Formulation
Application IHC
Other Names I kappa B alpha,I-kappa-B-alpha,IkappaBalpha,IkB-alpha,IKBA,IKBA,IKBalpha,MAD 3,MAD3,NF kappa B inhibitor alpha,NFKBI,IKB alpha
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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