Anti-Rat CD86 Polyclonal Antibody

Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01992
Size 100μl
Host Type Rabbit
Immunogen Recombinant humanT-lymphocyte activation antigen CD86 protein
Specificity Expressed by activated B-lymphocytes and monocytes.
Isotype IgG
Reacitivity Rat
Clone
Uniprot P42081
Concentration 2 mg/mL
Dilution IHC 1:50-1:100
Formulation
Application IHC
Other Names Activation B7-2 antigen 3,Activation B7-2 antigen,B-lymphocyte activation antigen B7-2 2,B-lymphocyte activation antigen B7-2,B7 2,B7,B7-2,B7.2,B70,B72 antigen,BU63,CD28 antigen ligand 2 2,CD28 antigen ligand 2,Cd28l2,CD28LG2,CD86,CD86 antigen,CD86 antigen,CD86 molecule,CD86,CLS1,CTLA-4 counter-receptor B7.2 2,3,CTLA-4 counter-receptor B7.2,Early T-cell costimulatory molecule 1,ETC-1,FUN 1,FUN-1,LAB72,Ly-58,Ly58,MB7,MB7-2,Membrane glycoprotein,MGC34413,T-lymphocyte activation antigen CD86,TS/A-2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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