Anti-Mouse/Rat DNAL1 Polyclonal Antibody

Part of the multisubunit axonemal ATPase complexes that generate the force for cilia motility and govern beat frequency (By similarity). Component of the outer arm dynein (ODA). May be involved in a mechanosensory feedback mechanism controlling ODA activity based on external conformational cues by tethering the outer arm dynein heavy chain (DNAH5) to the microtubule within the axoneme (By similarity). Important for ciliary function in the airways and for the function of the cilia that produce the nodal flow essential for the determination of the left-right asymmetry (PubMed:21496787).
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01980
Size 100μl
Host Type Rabbit
Immunogen Recombinant Dynein light chain 1, axonemal protein
Specificity Expressed in tissues carrying motile cilia such as testis.
Isotype IgG
Reacitivity Mouse,Rat
Clone
Uniprot Q4LDG9
Concentration 2 mg/mL
Dilution IHC 1:50-1:100
Formulation
Application IHC
Other Names axonemal,Axonemal dynein light chain 1,Axonemal dynein light chain,C14orf168,Chromosome 14 open reading frame 168,CILD16,DNAL 1,dnal1,DNAL1,Dynein axonemal light chain 1,Dynein light chain 1,Dynein light chain 1 axonemal,MGC12435
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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