Anti-Mouse IGF2BP2 Polyclonal Antibody

RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation (By similarity). Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. Binds to beta-actin/ACTB and MYC transcripts.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02009
Size 100μl
Host Type Rabbit
Immunogen Recombinant human Insulin-like growth factor 2 mRNA-binding protein 2 protein
Specificity Expressed in oocytes, granulosa cells of small and growing follicles, Leydig cells, spermatogonia and semen (at protein level). Expressed in testicular cancer (at protein level). Expressed weakly in heart, placenta, skeletal muscle, bone marrow, colon, kidney, salivary glands, testis and pancreas. Detected in fetal liver, fetal ovary, gonocytes and interstitial cells of the testis.
Isotype IgG
Reacitivity Mouse
Clone
Uniprot Q9Y6M1
Concentration 2 mg/mL
Dilution IHC 1:50-1:100
Formulation
Application IHC
Other Names Hepatocellular carcinoma autoantigen p62,IF2B2,IGF 2 mRNA binding protein 2,IGF II mRNA binding protein 2,IGF-II mRNA-binding protein 2,IGF2 mRNA-binding protein 2,Igf2bp2,IMP 2,IMP-2,IMP2,Insulin like growth factor 2 mRNA binding protein 2,Insulin-like growth factor 2 mRNA-binding protein 2,OTTHUMP00000082606,OTTHUMP00000082607,OTTHUMP00000082608,p62,VICKZ 2,VICKZ family member 2,VICKZ2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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