Anti-Mouse FCN1 Polyclonal Antibody

Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8 (PubMed:21037097). Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02015
Size 100μl
Host Type Rabbit
Immunogen Recombinant human Ficolin-1 protein
Specificity Peripheral blood leukocytes. Also detected in spleen, lung, and thymus, may be due to the presence of tissue macrophages or trapped blood in these tissues. Not detected on lymphocytes and granulocytes.
Isotype IgG
Reacitivity Mouse
Clone
Uniprot O00602
Concentration 2 mg/mL
Dilution IHC 1:50-1:100
Formulation
Application IHC
Other Names Collagen/fibrinogen domain containing protein 1,Collagen/fibrinogen domain-containing protein 1,Fcn1,FCN1,FCNM,ficolin (collagen/fibrinogen domain containing) 1,Ficolin 1,Ficolin A,Ficolin alpha,Ficolin-1,Ficolin-A,Ficolin-alpha,M ficolin,M-ficolin
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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