Anti-Human VDR Polyclonal Antibody

Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06119
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human VDR around the non-phosphorylation site of Ser208.
Specificity
Isotype IgG
Reacitivity Human
Clone
Uniprot P11473
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names 1 25 dihydroxyvitamin D3 receptor,1,1,25 dihydroxyvitamin D3 receptor,1,25-@dihydroxyvitamin D3 receptor,25-dihydroxyvitamin D3 receptor,Member 1,NR1I1,Nuclear receptor subfamily 1 group I member 1,PPP1R163,Protein phosphatase 1,regulatory subunit 163,VDR,VDR,Vitamin D (1,25- dihydroxyvitamin D3) receptor,Vitamin D hormone receptor,Vitamin D nuclear receptor variant 1,Vitamin D receptor,Vitamin D3 receptor
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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