Anti-Human USP44 Polyclonal Antibody

Deubiquitinase that plays a key role in the spindle checkpoint by preventing premature anaphase onset. Acts by specifically mediating deubiquitination of CDC20, a negative regulator of the anaphase promoting complex/cyclosome (APC/C). Deubiquitination of CDC20 leads to stabilize the MAD2L1-CDC20-APC/C ternary complex (also named mitotic checkpoint), thereby preventing premature activation of the APC/C.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06105
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human USP44
Specificity Expressed in testis.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q9H0E7
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:40000
Formulation
Application WB,ELISA
Other Names Deubiquitinating enzyme 44,E430004F17Rik,Ubiquitin carboxyl-terminal hydrolase 44,ubiquitin specific peptidase 44,Ubiquitin thiolesterase 44,Ubiquitin-specific-processing protease 44,UBP44,USP44
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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