Anti-Human TRIM25 Polyclonal Antibody

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11258
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human TRIM25
Specificity Ubiquitous.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q14258
Concentration 0.7 mg/mL
Dilution IHC 1:30-1:150
Formulation
Application IHC,ELISA
Other Names E3 ubiquitin/ISG15 ligase TRIM25,EFP,Estrogen responsive finger protein,Estrogen-responsive finger protein,RING finger protein 147,RNF 147,RNF147,TRI25,TRI25,TRIM 25,Trim25,Tripartite motif containing 25,Tripartite motif containing protein 25,Tripartite motif protein TRIM25,Tripartite motif-containing protein 25,Tripartite motifcontaining25,Ubiquitin/ISG15-conjugating enzyme TRIM25,Z147,Zinc finger protein 147 (estrogen responsive finger protein),Zinc finger protein 147,Zinc finger protein-147,ZNF 147,ZNF147
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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