Anti-Human TRIB3 Polyclonal Antibody

The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA07540
Size 100μl
Host Type Rabbit
Immunogen Full length fusion protein
Specificity Highest expression in liver, pancreas, peripheral blood leukocytes and bone marrow. Also highly expressed in a number of primary lung, colon and breast tumors. Expressed in spleen, thymus, and prostate and is undetectable in other examined tissues, including testis, ovary, small intestine, colon, leukocyte, heart, brain, placenta, lung, skeletal muscle, and kidney.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q96RU7
Concentration 0.7 mg/mL
Dilution IHC 1:30-150, ELISA 1:2000-10000
Formulation
Application IHC,ELISA
Other Names C20orf97,Neuronal cell death inducible putative kinase,Neuronal cell death-inducible putative kinase,NIPK,p65 interacting inhibitor of NF-kappaB,p65-interacting inhibitor of NF-kappa-B,SINK,SKIP 3,SKIP3,TRB 3,TRB-3,TRB3,TRIB 3,Trib3,TRIB3,Tribbles homolog 3,Tribbles pseudokinase 3,Tribbles3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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