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Anti-Human TREM1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06287
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human TREM-1
Specificity Highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. Also expressed in the lymph node, placenta, spinal cord and heart tissues. Expression is more elevated in peripheral blood leukocytes than in the bone marrow and in normal cells than malignant cells. Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. Strongly expressed in acute inflammatory lesions caused by bacteria and fungi. Isoform 2 was detected in the lung, liver and mature monocytes.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q9NP99
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-300, ELISA 1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names CD354,OTTMUSP00000018206,TREM 1,TREM-1,TREM1,TREM1,Triggering receptor expressed on monocytes 1,Triggering receptor expressed on myeloid cells 1,Triggering receptor TREM 1,Triggering receptor TREM1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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