Anti-Human TOP1MT Polyclonal Antibody

This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10712
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human TOP1MT
Specificity Ubiquitous; highest in skeletal muscle, heart, brain and fetal liver.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q969P6
Concentration 0.2 mg/mL
Dilution IHC 1:5-1:20
Formulation
Application IHC,ELISA
Other Names 2900052H09Rik,DNA topoisomerase I,DNA topoisomerase I,mitochondrial,mitochondrial,TOP1M,TOP1mt,Topoisomerase I mitochondrial
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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