Anti-Human TNFRSF21 Polyclonal Antibody

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11078
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human TNFRSF21
Specificity Highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. Detected at lower levels in lung, skeletal muscle, kidney, testis, uterus, small intestine, colon, spleen, bone marrow and fetal liver. Very low levels were found in adult liver and peripheral blood leukocytes.
Isotype IgG
Reacitivity Human
Clone
Uniprot O75509
Concentration 0.3 mg/mL
Dilution WB 1:500-1:2000
Formulation
Application WB,ELISA
Other Names TNFRSF 21,BM 018,BM018,CD358,Death receptor 6,DR 6,DR6,MGC31965,OTTHUMP00000039915,TNFR related death receptor 6,TNFRSF21,TNFRSF21 protein,TNR21,Tumor necrosis factor receptor superfamily member 21,Tumor necrosis factor receptor superfamily member 21 precursor
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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