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Anti-Human TNFRSF10B Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11349
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human TNFRSF10B
Specificity Widely expressed in adult and fetal tissues; very highly expressed in tumor cell lines such as HeLaS3, K-562, HL-60, SW480, A-549 and G-361; highly expressed in heart, peripheral blood lymphocytes, liver, pancreas, spleen, thymus, prostate, ovary, uterus, placenta, testis, esophagus, stomach and throughout the intestinal tract; not detectable in brain.
Isotype IgG
Reacitivity Human
Clone
Uniprot O14763
Concentration 0.3 mg/mL
Dilution WB 1:500-1:2000
Formulation
Application WB,ELISA
Other Names Fas like protein,Apoptosis inducing protein TRICK2A/2B,Apoptosis inducing receptor TRAIL R2,CD262,CD262 antigen,Cytotoxic TRAIL receptor 2,Death domain containing receptor for TRAIL/Apo 2L,Death receptor 5,DR5,KILLER,KILLER/DR5,OTTHUMP00000123492,OTTHUMP00000123493,p53 regulated DNA damage inducible cell death receptor(killer),TNF related apoptosis inducing ligand receptor 2,TNF-related apoptosis-inducing ligand receptor 2,TNFRSF10B,TR10B,TRAIL R2,TRAIL receptor 2,TRAIL-R2,TRAILR2,TRICK2,TRICK2A,TRICK2B,TRICKB,Tumor necrosis factor receptor like protein ZTNFR9,Tumor necrosis factor receptor superfamily member 10B,Tumor necrosis factor receptor superfamily,member 10b,ZTNFR9
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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