Anti-Human SLC22A6 Polyclonal Antibody

The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the sodium-independent uptake of 2,3-dimercapto-1-propanesulfonic acid (DMPS) By similarity.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02401
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the N-terminal region of human OAT1.
Specificity Strongly expressed in kidney and to a lower extent in liver, skeletal muscle, brain and placenta. Found at the basolateral membrane of the proximal tubule.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q4U2R8
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:20000
Formulation
Application WB,ELISA
Other Names FLJ55736,hOAT1,hPAHT,hROAT1,MGC45260,OAT1,Organic anion transporter 1,OTTHUMP00000236796,OTTHUMP00000236797,OTTHUMP00000236798,OTTHUMP00000236799,PAH transporter,PAHT,Para aminohippurate transporter,Renal organic anion transporter 1,ROAT1,S22A6,SLC22A6,Solute carrier family 22 (organic anion transporter) member 6,Solute carrier family 22 member 6
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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