Anti-Human SIPA1 Polyclonal Antibody

The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10177
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human SIPA1
Specificity Expressed in fetal as well as in adult tissues. Expressed abundantly in the lymphoid tissues such as thymus, spleen and peripheral blood lymphocytes and also shows a significant expression in the spinal cord.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q96FS4
Concentration 0.4 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names GTPase activating protein Spa 1,GTPase-activating protein Spa-1,MGC102688,MGC17037,p130 SPA-1,p130 SPA1,Signal induced proliferation associated 1,Signal induced proliferation associated gene 1,Signal induced proliferation associated protein 1,Signal-induced proliferation-associated protein 1,SIPA 1,Sipa-1,Sipa1,SIPA1,Spa1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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