Anti-Human SIN3B Polyclonal Antibody

Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription (By similarity).
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05134
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human Sin3B
Specificity
Isotype IgG
Reacitivity Human
Clone
Uniprot O75182
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IF 1:200-1:1000, ELISA 1:10000
Formulation
Application WB,IF,ELISA
Other Names Histone deacetylase complex subunit Sin3b,Paired amphipathic helix protein Sin3b,SIN3 homolog B transcription regulator,SIN3 transcription regulator family member B,SIN3 transcription regulator homolog B,Transcriptional corepressor Sin3b
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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