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Anti-Human SH2D2A Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes an adaptor protein thought to function in T-cell signal transduction. A related protein in mouse is responsible for the activation of lymphocyte-specific protein-tyrosine kinase and functions in downstream signaling. Alternative splicing results in multiple transcript variants.SH2D2A (SH2 Domain Containing 2A) is a Protein Coding gene. Among its related pathways are Development VEGF signaling via VEGFR2 - generic cascades and Immune response Fc epsilon RI pathway. GO annotations related to this gene include SH3 domain binding and SH3/SH2 adaptor activity. An important paralog of this gene is SH2D7.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04714
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human Lad
Specificity Expression limited to tissues of the immune system and, in particular, activated T-cells. Expressed in peripheral blood leukocytes, thymus and spleen. Much lower expression or undetectable, in brain, placenta, skeletal muscle, prostate, testis, ovary, small intestine, and colon. Expressed at low levels in unstimulated T-cells, but not expressed in normal resting or activated B-cells. According to PubMed:10692392, expression is not restricted to activated T-cells, but strongly expressed in blood cell lineages, the endothelium and other cell and tissue types, such as heart, lung, and liver.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q9NP31
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Formulation
Application WB,IHC-p,ELISA
Other Names F2771,SCAP,SH2 domain containing adapter protein,SH2 domain containing protein 2A,SH2 domain protein 2A,SH2 domain-containing adapter protein,SH2 domain-containing protein 2A,SH22A,Sh2d2a,T cell specific adapter protein,T cell specific adapter protein TSAd,T cell specific adpater protein TSAd,T cell-specific adapter protein,T lymphocyte specific adaptor protein,TSAd,VEGF receptor associated protein,VEGF receptor-associated protein,VRAP
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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