Anti-Human SCN4B Polyclonal Antibody

The protein encoded by this gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene.SCN4B (Sodium Voltage-Gated Channel Beta Subunit 4) is a Protein Coding gene. Diseases associated with SCN4B include Long Qt Syndrome-10 and Long Qt Syndrome 1. Among its related pathways are Neuropathic Pain-Signaling in Dorsal Horn Neurons and Developmental Biology. GO annotations related to this gene include ion channel binding and voltage-gated sodium channel activity. An important paralog of this gene is MPZL1.