Anti-Human RRAD Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

The protein may be important in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca2+ currents. As regulator of voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway and phosphorylation and activation of CAMK2D. Mostly expressed in the heart and muscle of type II diabetic humans. Also found in the skeletal muscle, lung and adipose tissue. Lesser amounts in placenta and kidney.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA05684
Size	100μl
Host Type	Rabbit
Immunogen	Synthesized peptide derived from the Internal region of human Rad GTPase
Specificity	Most abundantly expressed in the heart. Also found in the skeletal muscle and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans.
Isotype	IgG
Reacitivity	Human
Clone
Uniprot	P55042
Concentration	1mg/mL
Dilution	WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Formulation
Application	WB,IHC-p,IF,ELISA
Other Names	GTP binding protein RAD,GTP-binding protein RAD,RAD,RAD,RAD1,RAS (RAD and GEM) like GTP binding 3,Ras associated with diabetes,Ras related associated with diabetes,REM3,RRAD
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human RRAD Polyclonal Antibody

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