Anti-Human/Rat PKP2 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA05601
Size	100μl
Host Type	Rabbit
Immunogen	Synthesized peptide derived from the C-terminal region of human Plakophilin 2
Specificity	Detected in heart right ventricle (at protein level). Widely expressed. Found at desmosomal plaques in simple and stratified epithelia and in non-epithelial tissues such as myocardium and lymph node follicles. In most stratified epithelia found in the desmosomes of the basal cell layer and seems to be absent from suprabasal strata.
Isotype	IgG
Reacitivity	Human,Rat
Clone
Uniprot	Q99959
Concentration	1mg/mL
Dilution	WB 1:500-1:2000, ELISA 1:20000
Formulation
Application	WB,ELISA
Other Names	ARVD 9,ARVD9,PKP 2,PKP2,PKP2,Plakophilin-2,Plakophilin2
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Rat PKP2 Polyclonal Antibody

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