Anti-Human/Rat ARG1 Polyclonal Antibody

Liver arginase(Arginase-1) belongs to the arginase family. Hepatic arginase 1 is closely associated with alternative macrophage activation(PMID:12098359) and Arg1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia (ARGIN).
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01945
Size 100μl
Host Type Rabbit
Immunogen Recombinant Human Arginase-1 protein
Specificity Within the immune system initially reported to be selectively expressed in granulocytes (polymorphonuclear leukocytes [PMNs]) (PubMed:15546957). Also detected in macrophages mycobacterial granulomas (PubMed:23749634). Expressed in group2 innate lymphoid cells (ILC2s) during lung disease (PubMed:27043409).
Isotype IgG
Reacitivity Human,Rat
Clone
Uniprot P05089
Concentration 2 mg/mL
Dilution WB 1:500-1:1000
Formulation
Application WB
Other Names A I,Al,ARG 1,arg1,ARGI1,Arginase 1,Arginase liver,Arginase type I,Arginase,liver,Arginase-1,Arginase1,Liver type arginase,Liver-type arginase,Type I arginase
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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