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Anti-Human RASSF6 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05715
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human RASSF6
Specificity Highest expression in thymus, kidney and placenta. Also detected in colon, small intestine and lung. Tends to be down-regulated in 30-60% of tumors derived from breast, colon, kidney liver, rectum, pancreas, stomach and the thyroid gland compared to the normal counterpart.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q6ZTQ3
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:10000
Formulation
Application WB,ELISA
Other Names Putative RAS binding protein,Ras association (RalGDS/AF 6) domain family 6,Ras association (RalGDS/AF 6) domain family member 6,Ras association domain containing protein 6,Ras association domain family member 6
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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