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Anti-Human PTGDS Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA07076
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human PTGDS
Specificity Abundant in the brain and CNS, where it is expressed in tissues of the blood-brain barrier and secreted into the cerebro-spinal fluid. Abundantly expressed in the heart. In the male reproductive system, it is expressed in the testis, epididymis and prostate, and is secreted into the seminal fluid. Expressed in the eye and secreted into the aqueous humor. Lower levels detected in various tissue fluids such as serum, normal urine, ascitic fluid and tear fluid. Also found in a number of other organs including ovary, fimbriae of the fallopian tubes, kidney, leukocytes.
Isotype IgG
Reacitivity Human
Clone
Uniprot P41222
Concentration 0.2 mg/mL
Dilution IHC 1:15-1:50
Formulation
Application IHC,ELISA
Other Names Beta trace protein,Beta-trace protein,Cerebrin 28,Cerebrin-28,glutathione independent PGD synthase,Glutathione independent PGD synthetase,Glutathione-independent PGD synthase,L PGDS,Lipocalin type prostaglandin D synthase,Lipocalin-type prostaglandin-D synthase,LPGDS,PDS,PGD2,PGD2 synthase,PGDS,PGDS2,prostaglandin D synthase,prostaglandin D2 synthase (21 kDa,brain),prostaglandin D2 synthase (brain),prostaglandin D2 synthase 21kDa (brain),Prostaglandin D2 synthase,prostaglandin H2 D isomerase,Prostaglandin-D2 synthase,Prostaglandin-H2 D-isomerase,PTGDS,PTGDS,RP23-47P18.11-006
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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