Anti-Human PRSS3 Polyclonal Antibody

This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene.PRSS3 (Protease, Serine 3) is a Protein Coding gene. Diseases associated with PRSS3 include Thyroiditis and Pancreatitis. Among its related pathways are Collagen chain trimerization and Defensins. GO annotations related to this gene include calcium ion binding and serine-type peptidase activity. An important paralog of this gene is PRSS2.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06071
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human Trypsin-3.
Specificity Expressed in pancreas and brain. Also expressed in Paneth cells, at the base of small intestinal crypts.
Isotype IgG
Reacitivity Human
Clone
Uniprot P35030
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:40000
Formulation
Application WB,ELISA
Other Names Brain trypsinogen,Mesotrypsin,Mesotrypsinogen,MTG,Pancreatic trypsinogen III,Protease,serine,3,Protease,serine,4 (trypsin 4,brain),PRSS3,PRSS4,Serine protease 3,Serine protease 4,T9,TRY3,TRY3,TRY4,Trypsin 3,Trypsin III,Trypsin IV,Trypsin-3,Trypsinogen 4,Trypsinogen 5,Trypsinogen IV
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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