Anti-Human PRC1 Polyclonal Antibody

This gene encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated witHuman, Mouseitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04715
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide from human protein
Specificity Overexpressed in bladder cancer cells (PubMed:17409436).
Isotype IgG
Reacitivity Human
Clone
Uniprot O43663
Concentration 1mg/mL
Dilution WB 1:500-2000, ELISA 1:10000-20000
Formulation
Application WB,ELISA
Other Names Anaphase spindle elongation 1 homolog,ASE1,PRC1,PRC1,Protein regulating cytokinesis 1,Protein regulator of cytokinesis 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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