Anti-Human PPP1R13B Polyclonal Antibody

The protein plays a central role in regulation of apoptosis via its interaction with p53/TP53.Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo.It contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04949
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide from human protein
Specificity Reduced expression in breast carcinomas expressing a wild-type TP53 protein.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q96KQ4
Concentration 1mg/mL
Dilution IHC 1:50-200, ELISA 1:10000-20000
Formulation
Application IHC-p,ELISA
Other Names Apoptosis-stimulating of p53 protein 1,ASPP1,p53BP2 like,p85,Ppp1r13b,Protein phosphatase 1 regulatory subunit 13B
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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