Anti-Human PPM1F Polyclonal Antibody

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10743
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human PPM1F
Specificity
Isotype IgG
Reacitivity Human
Clone
Uniprot P49593
Concentration 0.8 mg/mL
Dilution WB 1:200-1:1000
Formulation
Application WB,ELISA
Other Names Ca(2+)/calmodulin-dependent protein kinase phosphatase,CaM-kinase phosphatase,CAMKP,CaMKPase,FEM 2,hFEM-2,KIAA0015,Partner of PIX 2,POPX2,PP2C phosphatase,Ppm1f,PPM1F,Protein fem-2 homolog,Protein phosphatase 1F (PP2C domain containing),Protein phosphatase 1F,Protein phosphatase Mg2+/Mn2+ dependent 1F
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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