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Anti-Human PIAS1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA09900
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human PIAS1
Specificity Expressed in numerous tissues with highest level in testis.
Isotype IgG
Reacitivity Human
Clone
Uniprot O75925
Concentration 0.2 mg/mL
Dilution WB 1:500-1:2000
Formulation
Application WB,ELISA
Other Names AR interacting protein,DDXBP1,DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1,DEAD/H box binding protein 1,DEAD/H box-binding protein 1,E3 SUMO-protein ligase PIAS1,GBP,Gu binding protein,Gu-binding protein,GU/RH-II,Pias1,PIAS1,Protein inhibitor of activated STAT protein 1,Protein inhibitor of activated STAT,1,RNA helicase II binding protein,RNA helicase II-binding protein,Zinc finger,MIZ-type containing 3,ZMIZ3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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