Anti-Human Phospho-IRF3 (Ser385) Polyclonal Antibody

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01864
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human IRF-3 around the phosphorylation site of Ser385
Specificity Expressed constitutively in a variety of tissues.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q14653
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names IIAE7,Interferon regulatory factor 3,IRF 3,IRF-3,IRF3,IRF3,MGC94729
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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