Anti-Human PDE5A Polyclonal Antibody

This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10661
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human PDE5A
Specificity Expressed in aortic smooth muscle cells, heart, placenta, skeletal muscle and pancreas and, to a much lesser extent, in brain, liver and lung.
Isotype IgG
Reacitivity Human
Clone
Uniprot O76074
Concentration 0.5 mg/mL
Dilution WB 1:200-1:1000, IHC 1:100-1:300
Formulation
Application WB,IHC,ELISA
Other Names 5''-cyclic phosphodiesterase,CGB PDE,CGB-PDE,CGBPDE,cGMP binding cGMP specific 3' 5' cyclic nucleotide phosphodiesterase,cGMP binding cGMP specific 35 cyclic nucleotide phosphodiesterase,cGMP binding cGMP specific phosphodiesterase,cGMP binding/cGMP specific phosphodiesterase,cGMP specific 3'5' cyclic phosphodiesterase,cGMP specific phosphodiesterase PDE5A2,cGMP specific phosphodiesterase type 5A,cGMP-binding cGMP-specific phosphodiesterase,cGMP-specific 3'',CN5A,CN5N,PDE 5,PDE 5A,PDE5,Pde5a,PDE5A,PDE5A1,Phosphodiesterase 5A,Phosphodiesterase 5A cGMP specific,Phosphodiesterase isozyme 5
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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