Anti-Human NUMA1 Polyclonal Antibody

This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05327
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the N-terminal region of human NuMA
Specificity
Isotype IgG
Reacitivity Human
Clone
Uniprot Q14980
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
Formulation
Application WB,IHC-p,ELISA
Other Names Centrophilin stabilizes mitotic spindle in mitotic cells,NMP 22,Nuclear matrix protein 22,Nuclear mitotic apparatus protein 1,Nuclear mitotic apparatus protein,NUMA 1,NUMA,NuMA protein,NUMA1,NUMA1,SP H antigen,SP-H antigen,Structural nuclear protein
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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