Anti-Human NOD2 Polyclonal Antibody

This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA09610
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human NOD2
Specificity Monocytes-specific.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q9HC29
Concentration 0.3 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names ACUG,Arthrocutaneouveal granulomatosis,BLAU,CARD15,Caspase recruitment domain family,member 15,Caspase recruitment domain protein 15,Caspase recruitment domain-containing protein 15,CD,CLR16.3,IBD1,Inflammatory bowel disease protein 1,LRR containing protein,NLR family,CARD domain containing 2,NLRC2,NOD like receptor C2,NOD2,NOD2 protein,NOD2,NOD2B,nucleotide binding oligomerization domain 2,Nucleotide binding oligomerization domain containing 2,Nucleotide binding oligomerization domain,leucine rich repeat and CARD domain containing 2,Nucleotide-binding oligomerization domain-containing protein 2,PSORAS1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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