Anti-Human NLRP9 Polyclonal Antibody

The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA08658
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human NLRP9
Specificity Expressed in ileum intestinal epithelial cells. Not detected in peripheral blood mononuclear cells (PubMed:28636595). Expressed in cerebral endothelial cells and, at much lower levels, in brain pericytes (PubMed:28432035).
Isotype IgG
Reacitivity Human
Clone
Uniprot Q7RTR0
Concentration 0.4 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names NACHT,LRR and PYD domains-containing protein 9,NALP9,NLRP9,Nucleotide-binding oligomerization domain protein 6,PYRIN and NACHT-containing protein 12
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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