Anti-Human NLRP7 Polyclonal Antibody

This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA09733
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human NLRP7
Specificity
Isotype IgG
Reacitivity Human
Clone
Uniprot Q8WX94
Concentration 0.5 mg/mL
Dilution IHC 1:100-1:300
Formulation
Application IHC,ELISA
Other Names CLR19.4,FLJ94610,HYDM,MGC126470,MGC126471,NACHT,leucine rich repeat and PYD containing 7,NACHT,LRR and PYD containing protein 7,NACHT,LRR and PYD domains containing protein 7,NACHT,LRR and PYD domains-containing protein 7,NALP7,NALP7,NLR family,pyrin domain containing 7,NLRP7,NOD12,Nucleotide-binding oligomerization domain protein 12,Nucleotide-binding oligomerization domain,leucine rich repeat and pyrin domain containing 7,PAN7,PYPAF3,PYRIN-containing APAF1-like protein 3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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