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Anti-Human NLRP6 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA08706
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human NLRP6
Specificity Expressed in peripheral blood leukocytes, predominantly in granulocytes and, at lower levels, in CD4(+) and CD8(+) T-cells. Expressed in colonic myofibroblasts (at protein level) (PubMed:21593405).
Isotype IgG
Reacitivity Human
Clone
Uniprot P59044
Concentration 0.6 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names Angiotensin II/vasopressin receptor,AVR,CLR11.4,NACHT,leucine rich repeat and PYD containing 6,NACHT,LRR and PYD containing protein 6,NACHT,LRR and PYD domains-containing protein 6,NAVR,NAVR/AVR,NLR family,pyrin domain containing 6,Nlrp6,NLRP6,Nucleotide binding oligomerization domain,leucine rich repeat and pyrin domain containing 6,PAN3,PYPAF5,PYRIN containing APAF1 like protein 5,PYRIN-containing APAF1-like protein 5
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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