Anti-Human NLRP4 Polyclonal Antibody

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP4, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes
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Properties

Data Sheet Click for Datasheet
Catalog Number PA08709
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human NLRP4
Specificity
Isotype IgG
Reacitivity Human
Clone
Uniprot Q96MN2
Concentration 0.5 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names Cancer/testis antigen 58,CLR19.5,CT58,FLJ32126,NACHT,leucine rich repeat and PYD containing 4,NACHT,LRR and PYD containing protein 4,NACHT,LRR and PYD domains-containing protein 4,NALP4,NLR family,pyrin domain containing 4,NLRP4,Nucleotide binding oligomerization domain,leucine rich repeat and pyrin domain containing 4,PAAD and NACHT containing protein 2,PAAD and NACHT-containing protein 2,PAN2,PYPAF4,PYRIN and NACHT-containing protein 2,PYRIN containing APAF1 like protein 4,PYRIN-containing APAF1-like protein 4,Ribonuclease inhibitor 2,RNH2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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