Anti-Human NKX3-1 Polyclonal Antibody

This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene.NKX3-1 (NK3 Homeobox 1) is a Protein Coding gene. Diseases associated with NKX3-1 include Chromosome 8P Deletion and Prostate Cancer. Among its related pathways are Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways and Pathways in cancer. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcription factor binding. An important paralog of this gene is NKX3-2.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05292
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the N-terminal region of human Nkx-3.1
Specificity Highly expressed in the prostate and, at a lower level, in the testis.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q99801
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names BAPX 2,BAPX2,Homeobox protein NK-3 homolog A,Homeobox protein Nkx 3.1,Homeobox protein Nkx-3.1,Homeobox protein Nkx3.1,NK homeobox (Drosophila) family 3 A,NK homeobox family 3 A,NK homeobox,family 3,member A,NK3 homeobox 1,NK3 transcription factor homolog A,NK3 transcription factor related locus 1,NKX 3,Nkx 3.1,NKX 3A,NKX3 1,NKX3,Nkx3-1,NKX3.1,Nkx3.1,mouse,homolog of,NKX31,NKX3A
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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