Anti-Human MUC6 Polyclonal Antibody

The MUC6 gene encodes gastric mucin, a secreted glycoprotein that plays an essential role in epithelial cytoprotection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA08649
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human MUC6
Specificity Expressed in the regenerative zone of gastric antrum, gastric body mucosa and gastric incisura mucosa. Expressed in the deeper mucous glands of gastric antrum. Overexpressed in Helicobacter pylori infected gastric epithelium. Highly expressed in duodenal Brunner's glands, gall bladder, seminal vesicle, pancreatic centroacinar cells and ducts, and periductal glands of the common bile duct.
Isotype IgG
Reacitivity Human
Clone
Uniprot Q6W4X9
Concentration 0.4 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names Gastric mucin 6,Gastric mucin-6,MUC 6,MUC-6,Muc6,MUC6 Fragment,MUC6 mucin,MUC6 mucin Fragment,MUC6,Mucin 6,Mucin 6 gastric,Mucin 6 oligomeric mucus/gel forming,Mucin glycoprotein Fragment,Mucin-6,Secretory mucin MUC6 Fragment
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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