Anti-Human MSH3 Polyclonal Antibody

The protein encoded by this gene forms a heterodimer witHuman, MouseSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex witHuman, MouseutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05133
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the N-terminal region of human MSH3
Specificity
Isotype IgG
Reacitivity Human
Clone
Uniprot P20585
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names Divergent upstream protein,DNA mismatch repair protein,DNA mismatch repair protein Msh 3,DNA mismatch repair protein MSH3,DUC 1,DUC1,DUG,DUP,hMSH3,MGC163306,MGC163308,Mismatch repair protein 1,MRP 1,MRP1,MSH 3,MSH3,MSH3,MutS homolog 3 (E. coli),MutS homolog 3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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